Xiaoai Lyu

Xiaoai Lyu is a researcher in molecular biology, cell biology, and genomics, with a focus on chromosomal instability, aneuploidy, and the molecular mechanisms underlying cancer progression. Using a combination of gene editing and bioinformatics tools, she investigates how abnormal chromosomal phenotypes alter cellular behavior.

Select Publications

• Akter, M., Lyu, X., …, Kang, J. (2025). Role of noncanonical histone H2A variant, H2A.Z, to maintain proper centromeric transcription and chromosome segregation, Journal of Biological Chemistry, J Biol Chem, 108464. doi.org/10.1016/j.jbc.2025.108464
• Huang, C. J., Lyu, X., & Kang, J. (2023). The molecular characteristics and functional roles of microspherule protein 1 (MCRS1) in gene expression, cell proliferation, and organismic development. Cell Cycle, 22(6), 619-632. doi:10.1080/15384101.2022.2145816
• Yang, H., Zhang, F., Huang, C. J., Lu, X., . . . Kang, J. (2019). Mps1 regulates spindle morphology through MCRS1 to promote chromosome alignment. Mol Biol Cell, 30(9), 1060-1068. doi:10.1091/mbc.E18-09-0546

Education

• PhD, Biology
  New York University
• MSc, Biology 
  New York University
• BSc, Applied Biology with Biotechnology
  Hong Kong Polytechnic University